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RefWork:Known vendors of cannabis testing instruments, software, and equipment

A variety of techniques are used to investigate the constituents of cannabis and their concentrations. From gas chromatography to make determinations about terpenes in a sample to quantitative polymerase chain reaction (qPCR) techniques to identify mycotoxins and microorganisms, these differing techniques require a wide variety of laboratory tools. The most common among cannabis testing instruments are chromatography and spectroscopy equipment, often combined together for a more complete analysis. However, this equipment can be expensive, sometimes prohibitively expensive. Initial investments may range anywhere from $75,000 up to $600,000 or more, depending on what sort of testing is being performed in the lab.[1][2][3] As such, new labs or labs looking to expand their analytic offerings to cannabis testing may also consider the purchase of previously owned equipment to save on initial start-up costs.

What follows is a list of vendors known to offer new and/or used instruments, software, and equipment commonly used in cannabis testing laboratories, with links to either the instruments marketed for cannabis testing or a landing page to begin a search. This is by no means a complete list but a representative example of the vendors marketing to the cannabis testing industry.

Contents

908 Devices, Inc.

Main landing page for cannabis testing: https://908devices.com/products/g908/

908 Devices, Inc. develops and distributes chemical analysis tools based on mass spectrometry. The company markets its G908 to the cannabis industry.

Instruments and methods

  • G908, a high-pressure mass spectrometry instrument for separation and quantitative analysis


AB Sciex Pte. Ltd.

Main landing page for cannabis testing: https://sciex.com/applications/food-and-beverage-testing/cannabis-testing

Commonly known as Sciex, AB Sciex Pte. Ltd. develops "solutions in mass spectrometry paired with capillary electrophoresis and liquid chromatography."[4] The company markets some of its solutions for cannabis lab testing, including[5]:

  • potency testing
  • mycotoxin testing
  • pesticide testing
  • terpene testing

Instruments and methods

Triple Quad systems

Sciex offers four different Triple Quad systems for tandem mass spectrometry paired with liquid chromatography (LC-MS/MS): the 6500+, 5500, 4500, and 3500. The company claims that with these systems "scientists can acquire multiple reaction monitoring (MRM), precursor, neutral loss, and product ion scans to develop powerful methods for complex matrices, all while maintaining reproducibility and robustness."[6]

QTRAP systems

Sciex also offers three different Triple Quad Linear Ion Traps (QTRAP) systems for LC-MS/MS: the 6500+, 5500, and 4500. The company states that these are similar to the Triple Quad systems "but with enhanced scan functions to enable simultaneous quantitation and confirmation."[7]

vMethod for Cannabis

Sciex also offers a "vMethod," a quantitation method for pesticide and cannabinoid analysis, that works on many of their LC-MS/MS systems.[8]


Agilent Technologies, Inc.

Main landing page for cannabis testing: https://www.agilent.com/en/promotions/cannabis

Agilent Technologies, Inc. is an instrument and software development company for the life sciences, diagnostics, and applied chemical industries. The company offers a variety of chromatography and spectrometry instruments (using a wide array of techniques) and software for the cannabis testing industry, including[9]:

  • potency and efficacy testing
  • heavy metals testing
  • pesticide testing
  • residual solvents testing
  • terpene testing

Instruments and methods

The company suggests instrument options based on what type of testing will occur.[9]

Potency and efficacy testing

Heavy metals testing

  • 5110 ICP-OES Instrument: an inductively coupled plasma optical emission spectrometry (ICP-OES) instrument with synchronous radial and axial measurement
  • 7800 ICP-MS: an inductively coupled plasma mass spectrometry (ICP-MS) instrument
  • 7900 ICP-MS: an inductively coupled plasma mass spectrometry (ICP-MS) instrument with higher matrix tolerance, wider dynamic range, and better signal-to-noise ratio
  • 8900 Triple Quadrupole ICP-MS: an inductively coupled plasma normal and tandem mass spectroscopy instrument with triple quadrupole

Pesticide testing

Residual solvents testing

Terpene testing

Software

  • ICP Expert Software for ICP-OES: inductively coupled plasma optical emission spectrometry (ICP-OES) software for data analysis
  • MassHunter: mass spectrometry software for instrument control, monitoring, and data analysis
  • MicroLab: fourier-transform infrared spectroscopy software for quantitative method development, calibrations, and data analysis


Alpha-CAT Lab s.r.o.

Main landing page for cannabis production: https://www.alpha-cat.org/the-test/how-it-works/

alpha-CAT Lab s.r.o. is a cannabis testing and equipment manufacturing business based in Prague, Czech Republic. The company not only runs cannabis testing laboratories in Europe but also develops the alpha-CAT cannabinoid analysis tool "which combines the simple analytical technique of thin-layer chromatography (TLC) with specific thin-layers and developing fluid."[10] Consult the website for more information.


BÜCHI Labortechnik AG

Main landing page for cannabis production: https://www.buchi.com/en/cannabis-application-booklet

BÜCHI Labortechnik AG is laboratory technology development company for research and development, quality control, and production operations globally. The company offers a variety of instruments and equipment for cannabis production workflow, including[11]:

  • post-chromatography and post-extraction solvent concentration
  • preperative chromatography for purification of cannabinoids
  • microencapsulation of CBD into gelatin beads/soft oil core capsules
  • formulation of CBD into an inhalable/edible dry powder

See the Theory & Applications booklet (main landing page) for more details on how to integrate the equipment for each activity.

Instruments and methods

The company suggests instrument options based on what type of production activity will occur.[11]

Post-chromatography and post-extraction solvent concentration

Preparative chromatography for purification of cannabinoids

Microencapsulation of CBD into gelatin beads/soft oil core capsules

Formulation of CBD into an inhalable/edible dry powder


CEM Corporation

Main landing page for cannabis testing: http://cem.com/cannabis

CEM Corporation is laboratory instrumentation and method design and development company, with a focus on compositional analysis of food and other samples, as well acid digestion and chemical synthesis. CEM specifically offers two different instruments for cannabis testing and analysis labs, including instruments for the[12]:

  • extraction for potency, pesticide, terpene, and mycotoxin testing
  • microwave digestion of oils, edibles, and plant material (before, e.g., inductively coupled plasma mass spectroscopy)

Instruments and methods

  • EDGE: an automated instrument for energized dispersive extraction and dispersive solid-phase extraction (dSPE)
  • MARS 6: a microwave digestion system with hundreds of preprogrammed methods


Emerald Scientific, LLC

Main landing page for cannabis testing: https://emeraldscientific.com/

Emerald Scientific, LLC calls their business "[t]he first and only company 100% dedicated to distributing scientific supplies and equipment to the cannabis industry."[13] The company lists a wide variety of instruments, equipment, and consumables for cannabis testing, production, and extraction laboratories. Emerald acts as a distributor of other products, and thus the inventory may change. Examples of inventory include:

  • sample preparation supplies
  • solvents
  • mass spectrometry columns
  • heating mantles
  • chillers and circulators
  • vacuum pumps and tubing
  • reference standards
  • culture media
  • safety equipment

Consult the Emerald website to see all they offer.


Fritsch GmbH

Main landing page for cannabis testing: https://www.fritsch-international.com/sample-preparation/applications-solutions/ (select "Cannabis" from Industry option)

Fritsch GmbH manufactures sample preparation and particle sizing equipment for laboratories. The company lists one instrument specifically for the cannabis industry.

Instruments and methods

  • Universal Cutting Mill PULVERISETTE 19: a cutting mill "to finely mill cannabis plant material in preparation for SFE processes," noting that "[t]he efficient and precise reduction in particle size optimizes oil output and formulation."[14]


GemmaCert Ltd.

Main landing page for cannabis testing: https://gemmacert.com/

GemmaCert Ltd. is a cannabis testing technology company that markets the GemmaCert analysis tool.

Instruments and methods

  • GemmaCert: a portable near-infrared spectroscopy instrument designed to analyze total THC and total CBD levels, without destroying the inserted specimen[15]; see the specifications sheet for more information


GenTech Scientific, Inc.

Main landing page for cannabis testing: https://gentechscientific.com/214-cannabis-testing-instruments

GenTech Scientific, Inc. is a distributor of refurbished laboratory analytical instruments. The company states they "guarantee OEM standards at a fraction of the cost of new instruments, and we provide one year warranty on all GenTech certified used lab instruments."[16] Top instruments include chromatography and spectrometry equipment, and GenTech also offers new consumable kits. Inventory changes regularly, so visit their website often for the latest.

LGC Limited

Main landing page for cannabis testing: https://us.lgcstandards.com/US/en/search?text=cannabis

LGC Limited—operating as LGC Standards—manufactures and distributes reference materials and proficiency testing schemes for a variety of industries. Among its offerings are cannabis-related testing reference standards for pesticides, residual solvents, and terpenes. Consult the vendor's web store or contact them directly to learn about their entire stock of reference materials.


Marshall Scientific, LLC

Main landing page for cannabis testing: https://www.marshallscientific.com/Cannabis_Testing_Laboratory_Equipment_a/1582.htm

Marshall Scientific, LLC is a distributor of refurbished laboratory equipment for a variety of clinical and research laboratories. The company markets some of its refurbished equipment for cannabis extraction and testing activities, including:

  • high-performance liquid chromatography systems
  • rotary evaporators
  • benchtop centrifuges
  • vacuum ovens
  • analytical balances
  • micropipette sets

Stock changes regularly, so visit their website often for the latest.

Microbiologics, Inc.

Main landing page for cannabis testing: http://www.microbiologics.com/cannabis

Microbiologics, Inc. develops and distributes biometerials. Among them, the company markets equipment and consumables for microbial testing of cannabis. Materials for growing reference cultures, bundled sets and panels of microorganisms, self-contained strains, and molecular standards are among Microbiologics' offerings. Consult their website for more details.

Neutec Group, Inc.

Main landing page for cannabis testing: https://www.neutecgroup.com/cannabis

Neutec Group, Inc. provides equipment and support services to quality control and research and development laboratories. Neutec offers equipment solutions for cannabis testing labs testing for microbiological contaminates and water activity. This includes colony counters, water activity meters, multispectral imaging solutions, and air samplers. Consult their website for more details.


Orange Photonics, Inc.

Main landing page for cannabis testing: http://www.orangephotonics.com/

Orange Photonics, Inc. ia a cannabis testing technology company that markets the LightLab cannabis analyzer.

Instruments and methods

  • LightLab: a portable high-performance liquid chromatography selective separation spectroscopy instrument for cannabis potency analysis; the optional Terpenes+ module also allows for terpenes analysis.[17]


Peak Scientific Instruments Ltd.

Main landing page for cannabis testing: https://www.peakscientific.com/blog/what-are-the-most-common-forms-of-cannabis-analysis/

Peak Scientific Instruments Ltd. designs, manufactures, and distributes high-performance gas generators for laboratories. In a November 2018 blog post, the company outlined how its many gas generation solutions could be paired with specific third-party analytical instruments for the various types of cannabis testing.[18] Peak offers solutions for:

  • potency and efficacy testing
  • heavy metals testing
  • mycotoxins analysis
  • pesticide testing
  • residual solvents testing
  • terpene testing

Instruments and methods

The company suggests gas generation options based on what type of testing will occur.[18]

Potency and efficacy testing

  • Precision series: modular gas generators for gas chromatography, including nitrogen, hydrogen, zero air, and compressed air gas generators; recommends pairing with Agilent Intuvo 9000 GC and Agilent 5977B GC/MSD instruments
  • Solaris XE 35: a nitrogen generator for liquid chromatography mass spectrometry or low-flow nitrogen instruments; recommends pairing with the various Agilent 1290 Infinity II series instruments

Heavy metals testing

  • Precision Hydrogen Trace 250: a hydrogen generator designed primarily for gas chromatography carrier gas use, as well as flame ionization and flame photometric detection, and inductively coupled plasma mass spectrometry; recommends pairing with the Agilent 7800/7900 ICP-MS and Agilent 8900 Triple Quadrupole ICP-MS
  • NG5000 and NG5000A: ultra-high purity nitrogen generators, with the NG5000A having its own internal compressor; recommends pairing with the Agilent 5110 ICP-OES

Mycotoxins analysis

  • Infinity 1051, Genius 1051, and Genius 3051: nitrogen and dry air generators for liquid chromatography mass spectrometry, with the 3051 being recommend over the 1051 if high-flow gas delivery mode is required; recommends pairing with the Shimadzu LCMS-8050 Triple Quadrupole Mass Spectrometer
  • Genius 1024 and Infinity 1031: nitrogen and dry air generators for liquid chromatography mass spectrometry; recommends pairing with the SCIEX Triple Quad or QTRAP 6500+ system

Pesticide testing

  • Infinity 1051, Genius 1051, and Genius 3051: nitrogen and dry air generators for liquid chromatography mass spectrometry, with the 3051 being recommend over the 1051 if high-flow gas delivery mode is required; recommends pairing with the Shimadzu LCMS-8050 Triple Quadrupole Mass Spectrometer
  • Genius 1024, Genius AB-3G, and Infinity 1031: nitrogen and dry air generators for liquid chromatography mass spectrometry; recommends pairing with the SCIEX ExionLC AC HPLC System, in conjunction with the SCIEX QET 4500 LC-MS/MS System
  • Precision series: modular gas generators for gas chromatography, including nitrogen, hydrogen, zero air, and compressed air gas generators; recommends pairing with Agilent Intuvo 9000 GC and Agilent 5977B GC/MSD instruments; recommends pairing with the Agilent 7000 Series Triple Quadrupole GC/MS and the Agilent GC/MS/MS Pesticides Analyzer
  • Solaris XE 35 and Genius XE 35: a nitrogen generator for liquid chromatography mass spectrometry or low-flow nitrogen instruments, as well as evaporative light scattering detection in the case of the Genius; recommends pairing with the Agilent 6400 Series Triple Quadrupole LC/MS
  • Solaris XE 35, Infinity XE 5010, Genius XE 35, and Genius XE 70: nitrogen generators for various purposes, depending on the model, though largely liquid chromatography mass spectrometry and evaporative light scattering detection; recommends pairing with the Agilent 6500 Series Accurate-Mass Quadrupole Q-TOF LC/MS

Residual solvents testing

  • Precision Nitrogen Headspace 250: a nitrogen generator for gas chromatography with headspace sampler requirements; recommends pairing with the Shimadzu Nexis GC-2030 with HS-20 Headspace Sampler or the GCMS-TQ8050 with Headspace Sampler
  • Precision series: modular gas generators for gas chromatography, including nitrogen, hydrogen, zero air, and compressed air gas generators; recommends pairing with Agilent 7890 Series GC and the Agilent Flame Ionization Detector

Terpene testing

  • Precision series: modular gas generators for gas chromatography, including nitrogen, hydrogen, zero air, and compressed air gas generators; recommends pairing with the Shimadzu GCMS-TQ8050 Triple Quadrupole Gas Chromatograph Mass Spectrometer, the Agilent Intuvo 9000 GC, and the Agilent 7890 Series GC
  • Genius 1024 and Infinity 1031: nitrogen and dry air generators for liquid chromatography mass spectrometry; recommends pairing with the SCIEX Triple Quad or QTRAP 6500+ system
  • Solaris XE 35: a nitrogen generator for liquid chromatography mass spectrometry or low-flow nitrogen instruments; recommends pairing with the Agilent 1260 Infinity II Diode Array Detector


PerkinElmer, Inc.

Main landing page for cannabis testing: http://www.perkinelmer.com/category/cannabis-analysis

PerkinElmer, Inc. is a scientific technology company developing and distributing solutions "for better detection, imaging, and informatics" in the laboratory.[19] The company discusses the research area of cannabis analysis on its website, recommending instrument and consumables solutions for cannabis testing laboratories, including[20]:

  • potency and efficacy testing
  • heavy metals testing
  • mycotoxins analysis
  • pesticide testing
  • residual solvents testing
  • terpene testing

Instruments and methods

The company suggests instrument options based on what type of testing will occur.[20]

Potency and efficacy testing

  • Flexar HPLC: a high-performance liquid chromatography system, that can be used with a quaternary pump, autosampler with Peltier cooling, column heater, and photodiode array detector to detect cannabinoids
  • Spectrum Two FTIR: a fourier transform near-infrared spectrometry device that uses nondestructive methods

Heavy metals testing

  • NexION ICP-MS, with a Titan MPS: an inductively coupled plasma mass spectroscopy device that can be used in conjunction with the Titan MPS microwave digestion processing tool

Mycotoxins analysis

  • QSight 220: an ultra-high-performance liquid chromatography tandem mass spectrometry instrument

Pesticide testing

  • QSight 220: an ultra-high-performance liquid chromatography tandem mass spectrometry instrument

Residual solvents testing

Terpene testing

Software

  • iLab: a laboratory execution system that automates testing, data collection, and reporting
  • ChemDraw: software for drawing chemical structures and biological pathways
  • Simplicity 3Q: software for workflow management


Quantum Analytics, LLC

Main landing page for cannabis testing: https://www.lqa.com/markets/cannabis/

Quantum Analytics is a distributor of laboratory analytical instruments. The company markets several of its third-party instruments to cannabis laboratories for applications such as[21]:

  • potency and efficacy testing
  • heavy metals testing
  • mycotoxins analysis
  • pesticide testing
  • residual solvents testing
  • terpene testing

Consult their website or cannabis capabilities flyer for more information.


Restek Corporation

Main landing page for cannabis testing: https://www.restek.com/Landing-Pages/Cannabis

Restek Corporation develops and manufactures chromatography columns and accessories for a wide variety of industries. The company offers a wide variety of supplies for the cannabis testing industry, including[22]:

  • chromatography columns
  • certified reference standards
  • sample preparation and management supplies
  • consumables and accessories for chromatography instruments

Consult their website or catalog to review all their cannabis testing supplies.


Sage Analytics

Main landing page for cannabis testing: http://sageanalytics.com/

Sage Analytics develops and manufactures potency testing solutions for the cannabis testing industry.

Instruments and methods

  • Profiler II Humboldt Special Edition: a portable near-infrared spectroscopy device for testing cannabis potency
  • Profiler II Humboldy Mini: same as the Special Edition but smaller and more lightweight
  • Beacon: a portable near-infrared spectroscopy device for testing cannabis potency, with an onboard touchscreen; also comes without a touchscreen, marketed as the Luminary Profiler


Scientific Repair, Inc.

Main landing page for cannabis testing: https://www.srigc.com/cn/downloads/1/Model420GCSept2016%20(2).pdf

Commonly known as SRI Instruments, Scientific Repair, Inc. manufactures and distributes chromatography instruments and accessories. Their 26-page guide on gas chromatographs for cannabis testing lists three primary instruments and describes their practical use for[23]:

  • potency and efficacy testing
  • residual solvents testing
  • terpene testing

Instruments and methods

The company suggests instrument options based on what type of testing will occur.[23]

Potency and efficacy testing

  • Model 310C-MM: a gas chromatography with flame ionization detection instrument, with additional columns for extended analyses
  • Model 420 GC: a gas chromatography with flame ionization detection instrument
  • Model 8610C: a gas chromatography with flame ionization detection instrument, with optional columns for additional analyses

Residual solvents testing

  • Model 310C-MM: a gas chromatography with flame ionization detection instrument, with additional columns for extended analyses
  • Model 8610C: a gas chromatography with flame ionizati
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